Antibody-Dependent Cellular Cytotoxity

ADCC potency increases of over 100-fold can be typically achieved with GlycoMAb® with the lowest being about 10-fold and the highest 10,000-fold, depending on the antibody and target cell. In the standard ADCC potency assay, target cells, antibody and freshly isolated immune effector cells are incubated together. After a few hours, the fraction of antibody-dependent target cell killing is determined.